Ownership Profile

Shareholder Breakdown
Shareholder Holders Values ($) % O/S Shares
Institution 142 283 72.27 103,900,309
Mutual Fund 131 69 23.12 33,239,981
Institutional Shareholder Rotation
Shareholder Holders Values Change ($) % O/S Shares Change
Buyers 55 12.68 3.20 4,603,148
Sellers 51 -7.48 1.88 -2,701,576
Net -- 5.19 1.32 1,901,572
Institutional Shareholder Concentration
Shareholder Values ($) % O/S Shares
Top 10 Inst. 242 61.73 88,757,312
Top 20 Inst. 262.70 66.99 96,320,344
Top 50 Inst. 277.48 70.73 101,684,917
Total Inst. 277.48 70.73 101,684,917
Institutional Shareholder Style
Shareholder Holders Values ($) % O/S Shares
Index 19 51 12.93 18,584,327
AggresGr 2 1 0.23 329,160
CoreGrowth 16 3 0.86 1,237,213
Growth 4 0 0.09 128,680
IncomeValue 1 1 0.22 314,463
Yield 2 0 0.02 22,000
BrokerDealer 18 4 1.12 1,616,916
GARP 13 46 11.56 16,615,784
HedgeFund 22 24 5.96 8,569,628
SectorSpecific 1 5 1.14 1,641,176
Specialty 1 0 0.01 12,173
CoreValue 12 69 17.16 24,669,794
DeepValue 5 1 0.35 498,093
Momentum 1 0 0.00 4,288
Top Holders: Institutional Investor
Holder Shares Held % O/S Shares Change Filing Date
Aurigene Discovery Technologies, Ltd. 27,328,464 19.01 10,208,333 09/07/2016
First Eagle Investment Management, L.L.C. 24,008,672 16.70 0 03/31/2017
Fidelity Management & Research Company 15,131,961 10.52 561,982 03/31/2017
BlackRock Institutional Trust Company, N.A. 8,656,502 6.02 -46,789 03/31/2017
The Vanguard Group, Inc. 4,827,625 3.36 304,268 03/31/2017
Millennium Management LLC 2,272,318 1.58 1,078,340 03/31/2017
Cormorant Asset Management LLC 2,000,000 1.39 -410,900 03/31/2017
State Street Global Advisors (US) 1,681,620 1.17 17,640 03/31/2017
Polar Capital LLP 1,641,176 1.14 121,050 03/31/2017
Northern Trust Investments, Inc. 1,208,974 0.84 29,758 03/31/2017
McNab (James R Jr) 1,179,688 0.82 -200,000 04/26/2017
Adage Capital Management, L.P. 1,040,000 0.72 5,000 03/31/2017
Geode Capital Management, L.L.C. 918,592 0.64 70,139 03/31/2017
RBC Capital Markets Wealth Management 896,002 0.62 46,206 03/31/2017
Nuveen LLC 831,893 0.58 -82,996 03/31/2017
D. E. Shaw & Co., L.P. 772,320 0.54 66,250 03/31/2017
Point72 Asset Management, L.P. 500,400 0.35 500,400 03/31/2017
Perceptive Advisors LLC 500,000 0.35 500,000 03/31/2017
Columbia Threadneedle Investments (US) 476,773 0.33 -27,674 03/31/2017
BlackRock Investment Management, LLC 447,364 0.31 -5,444 03/31/2017
Medical Strategy GmbH 389,742 0.27 -71,692 03/31/2017
Oppenheim Asset Management Services S.à r.l. 379,815 0.26 -92,051 03/31/2017
Renaissance Technologies LLC 348,600 0.24 -12,500 03/31/2017
BNY Mellon Asset Management 314,463 0.22 -17,587 03/31/2017
Vident Investment Advisory, LLC 303,908 0.21 56,041 03/31/2017
Allianz Global Investors U.S. LLC 285,551 0.20 285,551 03/31/2017
Bridgeway Capital Management, Inc. 269,160 0.19 -6,300 03/31/2017
Casdin Capital, LLC 230,000 0.16 230,000 03/31/2017
California State Teachers Retirement System 219,779 0.15 -9,900 03/31/2017
California Public Employees' Retirement System 210,300 0.15 -9,100 03/31/2017
Telemetry Investments, L.L.C. 202,905 0.14 17,905 03/31/2017
Focused Wealth Management, Inc. 187,250 0.13 0 03/31/2017
Charles Schwab Investment Management, Inc. 158,654 0.11 0 03/31/2017
Highbridge Capital Management, LLC 146,967 0.10 146,967 03/31/2017
Morgan Stanley & Co. LLC 146,246 0.10 -178,557 03/31/2017
Assenagon Asset Management S.A. 135,604 0.09 -14,582 05/31/2017
Weiss Multi-Strategy Advisers LLC 130,000 0.09 6,000 03/31/2017
Rhumbline Advisers Ltd. Partnership 125,189 0.09 5,024 03/31/2017
Janney Montgomery Scott LLC 123,644 0.09 12,344 03/31/2017
A.R.T. Advisors, LLC 122,850 0.09 84,890 03/31/2017
Goldman Sachs & Company, Inc. 117,758 0.08 -3,746 03/31/2017
Gray (Michael P) 107,304 0.07 0 01/31/2017
New York State Common Retirement Fund 101,501 0.07 1 03/31/2017
Two Sigma Investments, LP 94,925 0.07 19,969 03/31/2017
Wells Fargo Bank, N.A. 91,054 0.06 0 03/31/2017
Metropolitan Life Insurance Co. (US) 90,156 0.06 7,638 03/31/2017
ProFund Advisors LLC 87,861 0.06 -22,917 03/31/2017
Morgan Stanley Wealth Management 86,892 0.06 241 03/31/2017
Jacobs Levy Equity Management, Inc. 80,100 0.06 80,100 03/31/2017
Northern Trust Global Investments 76,395 0.05 0 03/31/2017

Ownership data is provided by Thomson Reuters, a third party service, and Curis, Inc. does not maintain or provide information directly to this service.