Ownership Profile

Shareholder Breakdown
Shareholder Holders Values ($) % O/S Shares
Institution 136 211 73.41 120,301,866
Mutual Fund 131 56 20.19 33,079,646
Institutional Shareholder Rotation
Shareholder Holders Values Change ($) % O/S Shares Change
Buyers 62 33.20 13.56 22,222,863
Sellers 60 -8.28 3.31 -5,428,087
Net -- 24.92 10.25 16,794,776
Institutional Shareholder Concentration
Shareholder Values ($) % O/S Shares
Top 10 Inst. 185 63.24 103,629,112
Top 20 Inst. 199.54 68.73 112,638,286
Top 50 Inst. 207.93 72.07 118,100,947
Total Inst. 207.93 72.07 118,100,947
Institutional Shareholder Style
Shareholder Holders Values ($) % O/S Shares
Index 19 30 12.18 19,958,266
AggresGr 2 1 0.24 393,760
CoreGrowth 16 22 9.15 14,993,712
Growth 4 0 0.07 120,627
IncomeValue 1 0 0.19 304,286
Yield 2 0 0.01 22,000
BrokerDealer 15 2 1.02 1,670,518
GARP 11 25 10.18 16,680,082
HedgeFund 17 7 2.83 4,644,907
SectorSpecific 1 4 1.58 2,587,623
Specialty 1 0 0.01 12,173
CoreValue 14 42 17.24 28,255,964
DeepValue 5 1 0.29 473,145
Momentum 1 0 0.00 4,288
Top Holders: Institutional Investor
Holder Shares Held % O/S Shares Change Filing Date
Aurigene Discovery Technologies, Ltd. 27,328,464 16.68 10,208,333 09/07/2016
First Eagle Investment Management, L.L.C. 26,508,672 16.18 2,500,000 09/30/2017
Fidelity Management & Research Company 14,169,478 8.65 -853,833 09/30/2017
Baird Investment Management 13,876,021 8.47 13,850,000 09/30/2017
BlackRock Institutional Trust Company, N.A. 8,968,147 5.47 116,736 09/30/2017
The Vanguard Group, Inc. 5,769,306 3.52 814,238 09/30/2017
Polar Capital LLP 2,587,623 1.58 300,000 09/30/2017
State Street Global Advisors (US) 1,857,167 1.13 123 09/30/2017
JP Morgan Asset Management 1,303,400 0.80 1,303,400 09/30/2017
Northern Trust Investments, Inc. 1,260,834 0.77 3,695 09/30/2017
McNab (James R Jr) 1,179,688 0.72 -200,000 04/26/2017
Cormorant Asset Management LLC 1,150,000 0.70 -850,000 09/30/2017
JPMorgan Private Bank (United States) 1,075,700 0.66 1,075,700 09/30/2017
Geode Capital Management, L.L.C. 1,058,036 0.65 132,360 09/30/2017
Perceptive Advisors LLC 951,201 0.58 0 09/30/2017
RBC Capital Markets Wealth Management 898,424 0.55 -46,061 09/30/2017
D. E. Shaw & Co., L.P. 839,912 0.51 120,298 09/30/2017
Bain Capital Public Equity, LP 682,125 0.42 682,125 09/30/2017
Vident Investment Advisory, LLC 656,529 0.40 19,894 09/30/2017
Nuveen LLC 517,559 0.32 -11,645 09/30/2017
BlackRock Investment Management, LLC 428,865 0.26 2,880 09/30/2017
Medical Strategy GmbH 389,742 0.24 0 07/31/2017
Bridgeway Capital Management, Inc. 388,160 0.24 304,000 09/30/2017
Oppenheim Asset Management Services S.à r.l. 354,815 0.22 -25,000 09/30/2017
Allianz Global Investors U.S. LLC 311,168 0.19 -719 09/30/2017
BNY Mellon Asset Management 304,286 0.19 -4,422 09/30/2017
Millennium Management LLC 218,429 0.13 218,429 09/30/2017
Goldman Sachs & Company, Inc. 213,559 0.13 93,921 09/30/2017
California Public Employees' Retirement System 210,300 0.13 0 09/30/2017
Telemetry Investments, L.L.C. 200,000 0.12 -2,500 09/30/2017
Focused Wealth Management, Inc. 185,513 0.11 -1,477 09/30/2017
California State Teachers Retirement System 181,703 0.11 -23,676 09/30/2017
PanAgora Asset Management Inc. 176,973 0.11 0 09/30/2017
Charles Schwab Investment Management, Inc. 158,654 0.10 0 09/30/2017
Morgan Stanley & Co. LLC 150,598 0.09 16,360 09/30/2017
Jacobs Levy Equity Management, Inc. 132,770 0.08 -22,700 09/30/2017
Rhumbline Advisers Ltd. Partnership 130,954 0.08 3,425 09/30/2017
Janney Montgomery Scott LLC 126,144 0.08 9,500 09/30/2017
Weiss Multi-Strategy Advisers LLC 125,000 0.08 0 09/30/2017
Fattaey (Ali) 115,890 0.07 50,000 11/15/2017
Gray (Michael P) 107,304 0.07 0 01/31/2017
New York State Common Retirement Fund 101,500 0.06 0 09/30/2017
OxFORD Asset Management 99,588 0.06 38,839 09/30/2017
Wells Fargo Bank, N.A. 99,135 0.06 8,081 09/30/2017
BlackRock Financial Management, Inc. 96,862 0.06 13,254 09/30/2017
BB&T Securities, LLC 96,522 0.06 1,550 09/30/2017
Deutsche Asset Management Americas 93,354 0.06 -15,815 09/30/2017
Morgan Stanley Wealth Management 89,865 0.05 -27 09/30/2017
ProFund Advisors LLC 89,008 0.05 4,966 09/30/2017
State of Wisconsin Investment Board 86,000 0.05 0 09/30/2017

Ownership data is provided by Thomson Reuters, a third party service, and Curis, Inc. does not maintain or provide information directly to this service.